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Accession Number PB2013-108838
Title Emergency Department Visits for Adverse Reactions Involving the Insomnia Medication Zolpidem.
Publication Date May 2013
Media Count 4p
Personal Author N/A
Abstract An estimated 50 to 70 million Americans suffer from chronic sleep disorders, which can affect performance on daily tasks and lead to negative health consequences. Zolpidem is a medication approved by the U.S. Food and Drug Administration (FDA) for short-term treatment of insomnia and is the active ingredient in the drugs Ambien, Ambien CR, Edluar, and Zolpimist. Historically, the FDA has recommended that the dose of most drugs containing zolpidem should be reduced by half when prescribed for the elderly. Despite this recommendation, studies have shown that older populations are often being prescribed the higher dose, which may increase adverse reactions. In a January 2013 safety announcement, the FDA took further steps by requiring drug manufacturers to lower the recommended doses of medications containing zolpidem by half for females; similar action was recommended, although not required, for males.
Keywords Adverse events
Elderly persons
Emergency medical services
Emergency visits
Health hazards
Sleep disorders
Zolpidem medication

Source Agency Substance Abuse and Mental Health Services Administration
NTIS Subject Category 57E - Clinical Medicine
57Q - Pharmacology & Pharmacological Chemistry
57T - Psychiatry
92B - Psychology
Corporate Author Substance Abuse and Mental Health Services Administration, Rockville, MD.
Document Type Technical report
Title Note N/A
NTIS Issue Number 1319
Contract Number N/A

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