Accession Number DE2012-1032522
Title Novel Insights into the Diversity of Catabolic Metabolism from Ten Haloarchaeal Genomes.
Publication Date 2011
Media Count 32p
Personal Author C. Scheuner I. Anderson K. Mavromatis M. Goker S. D. Hooper
Abstract We report here the comparative analysis of five newly sequenced haloarchaeal genomes with five previously published ones. Whole genome trees based on protein sequences provide strong support for deep relationships between the ten organisms. Using a soft clustering approach, we identified 887 protein clusters present in all halophiles. Of these core clusters, 112 are not found in any other archaea and therefore constitute the haloarchaeal signature. Four of the halophiles were isolated from water, and four were isolated from soil or sediment. Although there are few habitat-specific clusters, the soil/sediment halophiles tend to have greater capacity for polysaccharide degradation, siderophore synthesis, and cell wall modification. Halorhabdus utahensis and Haloterrigena turkmenica encode over forty glycosyl hydrolases each, and may be capable of breaking down naturally occurring complex carbohydrates. H. utahensis is specialized for growth on carbohydrates and has few amino acid degradation pathways. It uses the non-oxidative pentose phosphate pathway instead of the oxidative pathway, giving it more flexibility in the metabolism of pentoses.
Keywords Amino acids
Biofuels
Biological diversity
Biotechnology
Capacity
Carbohydrates
Catabolism
Cell wall
Comparative evaluations
Flexibility
Genome
Glycosyl hydrolases
Metabolism
Pentoses
Phosphates
Polysaccharides
Production
Proteins
Soils
Synthesis
Trees


 
Source Agency Technical Information Center Oak Ridge Tennessee
NTIS Subject Category 57B - Biochemistry
57F - Cytology, Genetics, & Molecular Biology
48D - Forestry
Corporate Author Department of Energy, Joint Genome Inst., Walnut Creek, CA. Genome Biology Program.
Document Type Technical report
Title Note N/A
NTIS Issue Number 1309
Contract Number N/A

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