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Accession Number DE2012-1032520
Title GenePRIMP: A GENE PRediction IMprovement Pipeline for Prokaryotic Genomes.
Publication Date 2010
Media Count 38p
Personal Author A. Pati G. Ovchinnikova N. Mikhailova N. N. Ivanova S. D. Hooper
Abstract We present GenePRIMP (Gene Prediction IMprovement Pipeline), A computational process that performs evidence-based evaluation of gene models in prokaryotic genomes and reports anomalies including inconsistent start sites, missed genes, and split genes. We show that manual curation of gene models using the anomaly reports generated by GenePRIMP improves their quality and demonstrate the applicability of GenePRIMP in improving finishing quality and comparing different genome sequencing and annotation technologies.
Keywords Anomalies
Computer models
Evaluation
Forecasting
Genes
Genome
Prokaryotic cells
Quality

 
Source Agency Technical Information Center Oak Ridge Tennessee
NTIS Subject Category 57F - Cytology, Genetics, & Molecular Biology
57B - Biochemistry
Corporate Author Department of Energy, Joint Genome Inst., Walnut Creek, CA. Genome Biology Program.
Document Type Technical report
Title Note N/A
NTIS Issue Number 1309
Contract Number N/A

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