Documents in the NTIS Technical Reports collection are the results of federally funded research. They are directly submitted to or collected by NTIS from Federal agencies for permanent accessibility to industry, academia and the public.  Before purchasing from NTIS, you may want to check for free access from (1) the issuing organization's website; (2) the U.S. Government Printing Office's Federal Digital System website; (3) the federal government Internet portal; or (4) a web search conducted using a commercial search engine such as
Accession Number DE2012-1032520
Title GenePRIMP: A GENE PRediction IMprovement Pipeline for Prokaryotic Genomes.
Publication Date 2010
Media Count 38p
Personal Author A. Pati G. Ovchinnikova N. Mikhailova N. N. Ivanova S. D. Hooper
Abstract We present GenePRIMP (Gene Prediction IMprovement Pipeline), A computational process that performs evidence-based evaluation of gene models in prokaryotic genomes and reports anomalies including inconsistent start sites, missed genes, and split genes. We show that manual curation of gene models using the anomaly reports generated by GenePRIMP improves their quality and demonstrate the applicability of GenePRIMP in improving finishing quality and comparing different genome sequencing and annotation technologies.
Keywords Anomalies
Computer models
Prokaryotic cells

Source Agency Technical Information Center Oak Ridge Tennessee
NTIS Subject Category 57F - Cytology, Genetics, & Molecular Biology
57B - Biochemistry
Corporate Author Department of Energy, Joint Genome Inst., Walnut Creek, CA. Genome Biology Program.
Document Type Technical report
Title Note N/A
NTIS Issue Number 1309
Contract Number N/A

Science and Technology Highlights

See a sampling of the latest scientific, technical and engineering information from NTIS in the NTIS Technical Reports Newsletter

Acrobat Reader Mobile    Acrobat Reader