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Accession Number
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DE2012-1032520
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Title
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GenePRIMP: A GENE PRediction IMprovement Pipeline for Prokaryotic Genomes.
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Publication Date
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2010
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Media Count
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38p
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Personal Author
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A. Pati G. Ovchinnikova N. Mikhailova N. N. Ivanova S. D. Hooper
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Abstract
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We present GenePRIMP (Gene Prediction IMprovement Pipeline), A computational process that performs evidence-based evaluation of gene models in prokaryotic genomes and reports anomalies including inconsistent start sites, missed genes, and split genes. We show that manual curation of gene models using the anomaly reports generated by GenePRIMP improves their quality and demonstrate the applicability of GenePRIMP in improving finishing quality and comparing different genome sequencing and annotation technologies.
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Keywords
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Anomalies
Computer models
Evaluation
Forecasting
Genes
Genome
Prokaryotic cells
Quality
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Source Agency
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Technical Information Center Oak Ridge Tennessee
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NTIS Subject Category
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57F - Cytology, Genetics, & Molecular Biology
57B - Biochemistry
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Corporate Author
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Department of Energy, Joint Genome Inst., Walnut Creek, CA. Genome Biology Program.
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Document Type
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Technical report
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Title Note
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N/A
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NTIS Issue Number
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1309
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Contract Number
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N/A
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