Documents in the NTIS Technical Reports collection are the results of federally funded research. They are directly submitted to or collected by NTIS from Federal agencies for permanent accessibility to industry, academia and the public.  Before purchasing from NTIS, you may want to check for free access from (1) the issuing organization's website; (2) the U.S. Government Printing Office's Federal Digital System website; (3) the federal government Internet portal; or (4) a web search conducted using a commercial search engine such as
Accession Number ADA587044
Title Development of a Biosensor Nanofluidic Platform for Integration with Terahertz Spectroscopic System.
Publication Date Jan 2013
Media Count 13p
Personal Author A. Moyer I. Sizov J. Ferrance T. Globus T. Khromova
Abstract A modified configuration for a THz stage has been designed, fabricated and assembled with the final goal to combine the THz spectrometer with a microfluidic platform for characterization of biological samples in solutions. The new stage accommodates a modified optical mounting system that focuses THz radiation on micro/nanofluidic chips with reduced size of 1.5 mm x 3.0 mm for the active region, encompassing 10 sample channels in parallel. Another important improvement to the stage is modified linear positioning of the microdetector with a probe relative to the microfluidic chip in a near field configuration. A significant change in the software for computer controlled operation has also been made. We continued protocol development for spectroscopic characterization of biomaterials using micro/nanofluidic chips. The algorithm for amplitude and frequency shift corrections has been investigated and tested. The possibility to further improve spectral resolution has been demonstrated.
Keywords Amplitude and frequency shift corrections
Biological detection
Biological material sensing
Micro nanofluidic spectroscopic platforms
Terahertz sensors

Source Agency Non Paid ADAS
NTIS Subject Category 72B - Algebra, Analysis, Geometry, & Mathematical Logic
99F - Physical & Theoretical Chemistry
Corporate Author Army Research Office, Research Triangle Park, NC.
Document Type Technical report
Title Note Final rept. 18 Sep-17 Dec 2012.
NTIS Issue Number 1405
Contract Number W911NF-12-C-0112

Science and Technology Highlights

See a sampling of the latest scientific, technical and engineering information from NTIS in the NTIS Technical Reports Newsletter

Acrobat Reader Mobile    Acrobat Reader