Accession Number ADA583372
Title Multifunctional Polymer Microbubbles for Advanced Sentinel Lymph Node Imaging and Mapping.
Publication Date Jun 2012
Media Count 6p
Personal Author A. P. Goodwin
Abstract The goal of this Postdoctoral Award was twofold. First, the proposed research sought to design microbubble ultrasound contrast agents with enhanced dye loading capacity for imaging and surgical labeling of sentinel lymph nodes. Second, the training plan sought to improve the PI's scientific development through a combination of junior scientist mentoring, grantwriting, and external presentations. Owing to poor yields and dispersities through the original proposed fabrication plan, a new synthesis plan led to some progress in creating uniform dye loading, although problems with yield remain. The PI also made progress in identifying polymer and chemical structures that break easily under ultrasound. On the training side, the PI has been quite successful in obtaining additional external funding through NIH, presenting at numerous conferences, and mentoring several students. In addition, he applied for multiple faculty positions, obtained three offers, and will begin a tenuretrack faculty position at the University of Colorado Boulder Department of Chemical and Biological Engineering in Summer 2012.
Keywords Biology
Breast cancer
Bubbles
Contrast
Dyes
Fabrication
Images
Instructors
Lymph nodes
Molecular structure
Multipurpose
Polymers
Position(Location)
Ultrasonics


 
Source Agency Non Paid ADAS
NTIS Subject Category 57E - Clinical Medicine
Corporate Author California Univ., San Diego, La Jolla.
Document Type Technical report
Title Note Annual summary rept. 15 Feb 2011-31 May 2012.
NTIS Issue Number 1401
Contract Number W81XWH-11-1-0215

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