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Accession Number ADA582943
Title Repair of Nerve Cell Membrane Damage by Calcium-Dependent, Membrane- Binding Proteins (Revised).
Publication Date Sep 2012
Media Count 20p
Personal Author C. E. Creutz
Abstract In the second year of this contract calcium-dependent, membrane- binding proteins of the annexin class were found to be effective at preventing damage and repairing damage to membranes caused by osmotic shock or other chemical and physical stresses using an in vitro assay involving synthetic membrane vesicles. These proteins may therefore be promising agents for protecting or promoting the repair of cell membranes in the case of spinal cord injury.
Keywords Annexins
Arachidonic acids
Calcium-dependent membrane-binding proteins
Lpa(Lysophosphatidic acid)
Membrane permeability barrier
Membrane repair
Nerve cell membrane damage
Nerve cells
Osmotic pressure
Spinal cord
Spinal cord injuries
Wounds and injuries

Source Agency Non Paid ADAS
NTIS Subject Category 57B - Biochemistry
57A - Anatomy
57S - Physiology
99D - Basic & Synthetic Chemistry
Corporate Author Virginia Univ., Charlottesville.
Document Type Technical report
Title Note Annual rept. 1 Sep 2011-31 Aug 2012.
NTIS Issue Number 1401
Contract Number W81XWH-10-1-0777

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