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Accession Number ADA582846
Title Plasma-Enhanced Copolymerization of Amino Acid and Synthetic Monomers.
Publication Date Dec 2011
Media Count 14p
Personal Author H. Jiang K. D. Anderson R. Jakubiak S. L. Young T. J. Bunning
Abstract In this paper we report the use of plasma-enhanced chemical vapor deposition (PECVD) for the simultaneous deposition and copolymerization of an amino acid with other organic and inorganic monomers. We investigate the fundamental effects of plasma-enhanced copolymerization on different material chemistries in stable ultrathin coatings of mixed composition with an amino acid component. This study serves to determine the feasibility of a direct, facile method for integrating biocompatible/active materials into robust polymerized coatings with the ability to plasma copolymerize a biological molecule (L-tyrosine) with different synthetic materials in a dry, one-step process to form ultrathin coatings of mixed composition. This process may lead to a method of interfacing biologic systems with synthetic materials as a way to enhance the biomaterial-tissue interface and preserve biological activity within composite films.
Keywords Amino acids
Chemical vapor deposition
Plasma enhanced copolymerization
Synthetic materials

Source Agency Non Paid ADAS
NTIS Subject Category 57B - Biochemistry
99D - Basic & Synthetic Chemistry
99C - Polymer Chemistry
71 - Materials Sciences
Corporate Author Georgia Inst. of Tech., Atlanta. School of Materials Science and Engineering.
Document Type Journal article
Title Note Journal article.
NTIS Issue Number 1401
Contract Number FA9550-08-1-0446 FA9550-09-1-0162

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