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Accession Number ADA575715
Title Analysis of Small Intestinal Microbiome in Children with Autism.
Publication Date Jan 2013
Media Count 5p
Personal Author R. Kushak
Abstract The goal of this project is to analyze the entire microbial population of the mucosa in the upper gastrointestinal tract of children with autism to determine if there is an overgrowth of specific populations of bacteria and analyze the relationship between the intestinal flora and behavior. Our current sub-contractor from the institute of Genome Sciences, University of Maryland School of Medicine was not able to amplify and sequence DNA from the duodenal biopsies of autistic children and controls. A new sub-contractor the Research and Testing Laboratory was found. A new set of duodenal biopsies from children with and without autism will be sent to the Research and Testing Laboratory for DNA extraction, PCR for 16S rRNA, sequencing. No additional funding will be requested to complete this project.
Keywords Behavior
Biopsy
Children
Deoxyribonucleic acids
Gastrointestinal system
Genome
Mental disorders
Microorganisms

 
Source Agency Non Paid ADAS
NTIS Subject Category 57A - Anatomy
57S - Physiology
57E - Clinical Medicine
Corporate Author Massachusetts General Hospital, Boston.
Document Type Technical report
Title Note Annual rept. 15 Dec 2012-14 Dec 2013.
NTIS Issue Number 1319
Contract Number W81XWH-10-1-0477

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