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Accession Number ADA575709
Title Neural Correlates of Restricted, Repetitive Behaviors in Autism Spectrum Disorders.
Publication Date Oct 2012
Media Count 5p
Personal Author D. Manoach S. Santangelo
Abstract During the period of 09/06/2011-09/05/2012, after obtaining MGH IRB approval for this project, we enrolled 17 subjects with ASD and 15 control subjects. Of these, one healthy control and two subjects with ASD were excluded for not meeting IQ inclusion criteria or inability to tolerate being in the scanner. For the remaining 29, we were able to acquire phenotyping data, ASD characterization (if applicable), anatomical images, DTI images, fMRI images, and genotyping data. Their phenotyping data and ASD characterization have all been updated onto REDCap, a free, secure, web-based application designed to support data capture for research studies. We also reconstructed structural MRI data, unpacked bold and DTI data, performed functional to structural registration, checked registration, performed quality control both during the scanning session and through PACE analysis, ran functional connectivity preprocessing and created seed files for future seed-specific functional connectivity analysis. Hence, data for the 29 subjects who completed the study are now ready for future analysis.
Keywords Behavior
Magnetic resonance imaging
Mental disorders
Nervous system

Source Agency Non Paid ADAS
NTIS Subject Category 57A - Anatomy
57S - Physiology
57E - Clinical Medicine
Corporate Author Massachusetts General Hospital, Boston.
Document Type Technical report
Title Note Annual rept. 6 Sep 2011-5 Sep 2012.
NTIS Issue Number 1319
Contract Number W81XWH-11-1-0774

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