Documents in the NTIS Technical Reports collection are the results of federally funded research. They are directly submitted to or collected by NTIS from Federal agencies for permanent accessibility to industry, academia and the public.  Before purchasing from NTIS, you may want to check for free access from (1) the issuing organization's website; (2) the U.S. Government Printing Office's Federal Digital System website; (3) the federal government Internet portal; or (4) a web search conducted using a commercial search engine such as
Accession Number ADA574630
Title Effect of a Hypocretin/Orexin Antagonist on Neurocognitive Performance.
Publication Date Sep 2012
Media Count 100p
Personal Author T. Neylan
Abstract During Year 3, revisions were made to the protocol, informed consent, and HIPAA documents to allow for additional data collection during the hospital portion of the study via actigraphy. Recruitment materials were also revised in order to target a non-smoking population. This greatly reduced the amount of participants ruled out during the phone screening process, improving phone screening success. Safety reports continue to be sent to Actelion on a monthly basis. Both blinded and unblinded monitoring visits of study procedures and facilities are ongoing. Throughout Year 3, many new study team members were hired and trained (Study Coordinator, Recruiter, Research Assistant, and Lab Manager). The study team also expanded to include additional informed consent administrators, clinical interviewers, as well as sleep technicians and neuropsychological assessment administrators in order to reach the new quarterly enrollment goal of 39 participants. Enrollment is expected to increase throughout Year 4 due to the actions taken above.
Keywords Clinical medicine
Data acquisition
Neurocognitive performance

Source Agency Non Paid ADAS
NTIS Subject Category 92B - Psychology
57T - Psychiatry
57E - Clinical Medicine
Corporate Author Northern California Inst. for Research and Education, San Francisco.
Document Type Technical report
Title Note Annual rept. 1 Sep 2010-31 Aug 2011.
NTIS Issue Number 1318
Contract Number W81XWH-09-2-0080

Science and Technology Highlights

See a sampling of the latest scientific, technical and engineering information from NTIS in the NTIS Technical Reports Newsletter

Acrobat Reader Mobile    Acrobat Reader