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Accession Number ADA570596
Title Ketamine as a Rapid Treatment for Post-Traumatic Stress Disorder.
Publication Date Oct 2012
Media Count 5p
Personal Author A. Feder D. Charney
Abstract Post-traumatic stress disorder (PTSD) is a debilitating anxiety disorder characterized by intrusive re-experiencing of the traumatic events, avoidance of situations and stimuli that could serve as reminders of these events, and chronic hypervigilance. Patients with PTSD are often also depressed, and many have significant memory impairments. In the present study, we expect a single ketamine infusion to reduce core PTSD symptoms. In addition, in those patients with PTSD who are depressed, we expect ketamine to reduce depressed mood. Finally, ketamine is known to impair memory function. We will also test if the extent of ketamine-induced memory impairment during the infusion can predict how well people do after the infusion. The first patient was randomized at the end of May 09 as recruitment began in March 09. To date, 40 people have been randomized of which 33 have completed study procedures.
Keywords Anxiety
Memory devices
Post traumatic stress disorder

Source Agency Non Paid ADAS
NTIS Subject Category 57E - Clinical Medicine
57W - Stress Physiology
92B - Psychology
Corporate Author Mount Sinai School of Medicine, New York.
Document Type Technical report
Title Note Annual rept. 14 Sep 2011-13 Sep 2012.
NTIS Issue Number 1315
Contract Number W81XWH-08-1-0602

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