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Accession Number ADA570565
Title Correlation Between Physicochemical Characteristics and Toxicological Properties of Nanomaterials.
Publication Date Jan 2012
Media Count 45p
Personal Author A. Elder G. Oberdoerster J. Finkelstein J. McGrath T. Gunter
Abstract Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles; Translocation of inhaled ultrafine manganese oxide particles to the central nervous system; Nanoparticle (NP) uptake by type I alveolar epithelial cells and their oxidant stress response; Toxicology of nanoparticles: A historical perspective; In vivo skin penetration of quantum dot nanoparticles in the murine model: The effect of UVR; Testing nanomaterials of unknown toxicity: An example based on Platinum nanoparticles of different shapes; Nanoparticles and the Brain: Cause for Concern; Concept of assessing nanoparticle hazards considering nano-particle dosemetric and chemical/biological response-metrics; Validation of an LDH assay for assessing nanoparticle toxicity; Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology.
Keywords Alveoli
Carbon nanotubes
Cell death
Central nervous system
Manganese oxides
Physicochemical properties
Quantum dots
Ultraviolet radiation

Source Agency Non Paid ADAS
NTIS Subject Category 57Y - Toxicology
99F - Physical & Theoretical Chemistry
71M - Miscellaneous Materials
Corporate Author Rochester Univ. Medical Center, NY.
Document Type Technical report
Title Note Final rept. Mar 2004-Dec 2011.
NTIS Issue Number 1315
Contract Number FA9550-04-1-0430

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