Accession Number ADA570529
Title Phonologically-Based Biomarkers for Major Depressive Disorder.
Publication Date Apr 2011
Media Count 16p
Personal Author A. C. Trevino N. Malyska T. F. Quatieri
Abstract Of increasing importance in the civilian and military population is the recognition of Major Depressive Disorder at its earliest stages and intervention before the onset of severe symptoms. Toward the goal of more effective monitoring of depression severity, we introduce vocal biomarkers that are derived automatically from phonologically-based measures of speech rate. To assess our measures, we use a 35-speaker free-response speech database of subjects treated for depression over a six-week duration. We find that dissecting average measures of speech rate into phone-specific characteristics and, in particular, combined phone-duration measures uncovers stronger relationships between speech rate and depression severity than global measures previously reported for a speech-rate biomarker. Results are supported by correlation of our measures with depression severity and classification of depression state with these vocal measures. Our approach provides a general framework for analyzing individual symptom categories through phonological units, and supports the premise that speaking rate can be an indicator of psychomotor retardation severity.
Keywords Clinical hamd
Depression
Military personnel
Phone
Population
Speech
Speech rate
Stress(Psychology)
Telephone systems
Vocal biomarkers


 
Source Agency Non Paid ADAS
NTIS Subject Category 92B - Psychology
57T - Psychiatry
45F - Verbal
Corporate Author Massachusetts Inst. of Tech., Lexington. Lincoln Lab.
Document Type Technical report
Title Note Article Apr-May 2011.
NTIS Issue Number 1315
Contract Number FA8720-05-C-0002

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