Documents in the NTIS Technical Reports collection are the results of federally funded research. They are directly submitted to or collected by NTIS from Federal agencies for permanent accessibility to industry, academia and the public.  Before purchasing from NTIS, you may want to check for free access from (1) the issuing organization's website; (2) the U.S. Government Printing Office's Federal Digital System website; (3) the federal government Internet portal; or (4) a web search conducted using a commercial search engine such as
Accession Number ADA570059
Title Clinically Realistic Large Animal Model of Intra-Articular Fracture.
Publication Date Oct 2012
Media Count 40p
Personal Author Y. Tochigi
Abstract The primary objective of this project is to develop a novel large animal survival model of intra-articular fracture (IAF) in which all major pathophysiological attributes of corresponding human clinical injuries are realistically replicated, and in which post-traumatic osteoarthritis (OA) predictively develops. Work during the reporting period (Year 1) has yielded definitive protocols to create a large animal survival IAF model and to document/analyze the natural course of fractured experimental joints in this model. In PY-3, documentation/analysis of the natural course data will be continued. Simultaneously, using the protocols established in the last two project years, the 7-day survival study to test the effect of a therapeutic treatment will be pursued.
Keywords Arthritis
Bone fractures
Wounds and injuries

Source Agency Non Paid ADAS
NTIS Subject Category 57A - Anatomy
57S - Physiology
57E - Clinical Medicine
Corporate Author Iowa Univ., Iowa City.
Document Type Technical report
Title Note Annual rept. 15 Sep 2011-14 Sep 2012.
NTIS Issue Number 1314
Contract Number W81XWH-10-1-0864

Science and Technology Highlights

See a sampling of the latest scientific, technical and engineering information from NTIS in the NTIS Technical Reports Newsletter

Acrobat Reader Mobile    Acrobat Reader