Accession Number ADA570059
Title Clinically Realistic Large Animal Model of Intra-Articular Fracture.
Publication Date Oct 2012
Media Count 40p
Personal Author Y. Tochigi
Abstract The primary objective of this project is to develop a novel large animal survival model of intra-articular fracture (IAF) in which all major pathophysiological attributes of corresponding human clinical injuries are realistically replicated, and in which post-traumatic osteoarthritis (OA) predictively develops. Work during the reporting period (Year 1) has yielded definitive protocols to create a large animal survival IAF model and to document/analyze the natural course of fractured experimental joints in this model. In PY-3, documentation/analysis of the natural course data will be continued. Simultaneously, using the protocols established in the last two project years, the 7-day survival study to test the effect of a therapeutic treatment will be pursued.
Keywords Arthritis
Bone fractures
Joints(Anatomy)
Osteoporosis
Pathology
Therapy
Wounds and injuries


 
Source Agency Non Paid ADAS
NTIS Subject Category 57A - Anatomy
57S - Physiology
57E - Clinical Medicine
Corporate Author Iowa Univ., Iowa City.
Document Type Technical report
Title Note Annual rept. 15 Sep 2011-14 Sep 2012.
NTIS Issue Number 1314
Contract Number W81XWH-10-1-0864

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