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Accession Number
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ADA566728
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Title
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Nano-Engineered Drug Combinations for Breast Cancer Treatment.
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Publication Date
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Jun 2012
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Media Count
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10p
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Personal Author
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J. Lahann
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Abstract
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We hypothesis that nanoparticles can increase the efficacy of combination therapies for cancer. The project aims to explore nanoparticle- based transport vehicles for effective delivery of two different cancer drugs. In particular, we aim to use two breast cancer drugs, which enhance each other s efficacy and use them as a model drug pair for the development of novel dual- drug nano-therapeutics. The research to date has been focused on extending existing electrohydrodynamic co-jetting technology in the Lahann lab towards the simultaneous release of two independent small molecule drug surrogates.
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Keywords
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Breast cancer Cargo vehicles Delivery Drugs Electrohydrodynamics Hypotheses Laboratories Molecules Nanoparticles Release Synchronism Therapy
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Source Agency
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Non Paid ADAS
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NTIS Subject Category
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57E - Clinical Medicine
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Corporate Author
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Michigan Univ., Ann Arbor.
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Document Type
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Technical report
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Title Note
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Annual rept. 15 May 2011-14 May 2012.
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NTIS Issue Number
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1307
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Contract Number
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W81XWH-11-1-0111
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