The NTIS website and supporting ordering systems are undergoing a major upgrade from 8PM on September 25th through approximately October 6. During that time, much of the functionality, including subscription and product ordering, shipping, etc., will not be available. You may call NTIS at 1-800-553-6847 or (703) 605-6000 to place an order but you should expect delayed shipment. Please do NOT include credit card numbers in any email you might send NTIS.
Documents in the NTIS Technical Reports collection are the results of federally funded research. They are directly submitted to or collected by NTIS from Federal agencies for permanent accessibility to industry, academia and the public.  Before purchasing from NTIS, you may want to check for free access from (1) the issuing organization's website; (2) the U.S. Government Printing Office's Federal Digital System website http://www.gpo.gov/fdsys; (3) the federal government Internet portal USA.gov; or (4) a web search conducted using a commercial search engine such as http://www.google.com.
Accession Number ADA566728
Title Nano-Engineered Drug Combinations for Breast Cancer Treatment.
Publication Date Jun 2012
Media Count 10p
Personal Author J. Lahann
Abstract We hypothesis that nanoparticles can increase the efficacy of combination therapies for cancer. The project aims to explore nanoparticle- based transport vehicles for effective delivery of two different cancer drugs. In particular, we aim to use two breast cancer drugs, which enhance each other s efficacy and use them as a model drug pair for the development of novel dual- drug nano-therapeutics. The research to date has been focused on extending existing electrohydrodynamic co-jetting technology in the Lahann lab towards the simultaneous release of two independent small molecule drug surrogates.
Keywords Breast cancer
Cargo vehicles
Delivery
Drugs
Electrohydrodynamics
Hypotheses
Laboratories
Molecules
Nanoparticles
Release
Synchronism
Therapy


 
Source Agency Non Paid ADAS
NTIS Subject Category 57E - Clinical Medicine
Corporate Author Michigan Univ., Ann Arbor.
Document Type Technical report
Title Note Annual rept. 15 May 2011-14 May 2012.
NTIS Issue Number 1307
Contract Number W81XWH-11-1-0111

Science and Technology Highlights

See a sampling of the latest scientific, technical and engineering information from NTIS in the NTIS Technical Reports Newsletter

Acrobat Reader Mobile    Acrobat Reader