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Accession Number
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ADA564418
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Title
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Development of a Novel Microfluidic Platform for Multiple Sclerosis Study.
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Publication Date
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Aug 2012
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Media Count
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6p
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Personal Author
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I. H. Yang
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Abstract
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Neural stem cells (NSC) are multipotent cells isolated from striatal tissue and the subventricular zone, which is one of a few neurogenic areas in the adult brain. Evidence suggests that NSC proliferation and differentiation occur under physiological conditions and can be enhanced in certain pathological conditions following neural damage. However, the communication between soluble factors of inflammatory T cells and NSCs that affect the proliferation and differentiation of NSCs remain unknown. The goal of this project is to develop a novel NSC culture platform that is capable of both compartmentalizing and fluidically isolating microdomains of NSCs.
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Keywords
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Brain
Cells(Biology)
Communication and radio systems
Cultures(Biology)
Damage
Multiple sclerosis
Nervous system
Nervous system diseases
Nsc(Neural stem cells)
Physiological effects
Stem cells
T lymphocytes
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Source Agency
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Non Paid ADAS
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NTIS Subject Category
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57E - Clinical Medicine
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Corporate Author
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Johns Hopkins Univ., Baltimore, MD.
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Document Type
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Technical report
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Title Note
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Final rept. 15 Jul 2011-14 Jul 2012.
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NTIS Issue Number
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1303
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Contract Number
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W81XWH-11-1-0610
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